Friday, October 3, 2025

Synthetic cannabis; deadly new opioid


Worse than fentanyl, carfentanil (Wildnil), tranq
Careful, kids. There's a new danger on the block. Nitazenes are a chemically defined class of substances derived from the parent compound nitazene. They were developed in the second half of the 1950s by the Swiss pharmaceutical giant Ciba AG as pain-relieving agents.

Big Pharma to blame for making obscene profits?
They are important as centrally active, selective μ-opioid receptor agonists. The high potency of fentanyl (in humans) is matched by only a few nitazenes and surpassed by etonitazene and isotonitazene.

Due to unacceptable side effects, nitazenes were never included in the pharmacopoeia of human or veterinary medicine.

Deadly fake weed Delta-8

Since 2019, highly potent nitazenes have proliferated as ″new synthetic opioids″ in the North American and European narcotics markets and as such have become a formative component of the opioid epidemic in the United States. Overdoses of nitazene opioids have led to several hundred documented fatalities [1].

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