Thursday, December 30, 2021

Insight into biology of death: 'brain tsunamis'


A new study may lend credence to what happens during the biological and irreversible death of the brain organ.

Published in the Annals of Neurology, the study inspected spreading depolarization of the human cerebral cortex and provided a better understanding of how the brain responds to energy depletion.

The depolarization of brain cells is likened to tsunamis in how violent they can be, like sporadic waves overtaking the nervous system and causing destruction on a grand scale.

Prince Siddhartha is shown travelling, when he first sees old age, sickness, and death.
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Although restoration of circulation is the primary goal in emergency treatment, researchers believe that understanding how the brain responds to energy depletion could help predict the time available for resuscitation "until irreversible damage" occurs in the brain.

"This potentially reversible, spreading wave typically starts 2 to 5 minutes after the onset of severe ischemia, marking the onset of a toxic intraneuronal change that eventually results in irreversible injury," the study states.

The methodology employed by researchers involved performing recordings with either electrode strips or electrode arrays in patients with devastating brain injury that resulted in activation of a "Do Not Resuscitate – Comfort Care" order. More

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