Showing posts with label cell. Show all posts
Showing posts with label cell. Show all posts

Tuesday, June 17, 2025

Life in a white cell: 'La Valigia'


LA VALIGIA || stop motion short film
Life in Hell (Matt Groening)
(Studio Croma AnimationBOLOGNA. An old man is sitting on the edge of a bed in a bare room with stoned walls, his face furrowed with deep wrinkles and his unkempt beard, gnarled hands still full of life, curved shoulders: he is alone and thoughtful. A small and ramshackle window with bars is the only outlet to the outside.

In front of him he has a mysterious suitcase. Opening it the man finds himself in his hands the photographs and the personal effects of a whole life. Thus begins the sequence of memories and visions, synapses of the mind that come to life and invade the room of the elderly bringing him back in time, first adult then boy, finally child.


Better than other La Valigias. PRIZES: -BornShort Film Festival 2014: Best Animation Award Corto Dorico 2014: Best short film -BazzaCinema 2015: Best Screenplay -Lo Spiraglio FF 2015: Best Film -Premio Morandini Corti d'Autore: Winner Nastri d'argento - Corti 2015: Fifth finalist David di Donatello 2015: Fifth finalist Kalat Nissa Film Festival 2015: Best Animation Film ShorTS Int. Maremetraggio 2015: Best Italian Production Cast Film Festival 2015: Special Award Best movies Pázmány Film Festival 2015: Best Italian Film Arno Stream Fest: Best short movie Genova Film Festival 2015: Critics Award Toko Film Festival 2015: Best Screenplay Metricamente Corto 2015: Best Screenplay Corto di Sera 2015: Special prize. F.N.C. Gold frame Ke Corto Film Festival 2015: Best animated short film Parma Intl. Music FF 2015: Best Renaissance 2.0 soundtrack DIRECTOR Pier Paolo Paganelli SUBJECT AND SCRIPT Laura Castaldini, Pier Paolo Paganelli WITH Roberto Herlitzka Rodolfo Bianchi Alex Polidori Riccardo Suarez PRODUCED BY Ivan Olgiati, Stefania Marconi, Daniele Paganelli ASSOCIATED PRODUCER Gloria Giorgianni per Anele PHOTOGRAPHY DIRECTOR Gianmarco Rossetti EDITING Davide Rossetti ARTISTIC DIRECTOR Guglielmo Trautvetter ANIMATION Giacomo Giuriato SOUNDTRACK Matteo Malferrari PUPPET MACKER Matteo Burani POST PRODUCTION Jacopo Gaustini, Luca Lazzarin DIGITAL VIDEO EFFECTS Sara Passuti SOUND Giovanni Frezza PROMOTION Stefania Marconi, Chiara Galloni DISTRIBUTION Paolo Pellicano.
  • Studio Croma Animation, "The Suitcase," Jan. 24, 2021; Ven. Yongey Mingyur Rinpoche; UnJaded Jade; Eds., Wisdom Quarterly

Thursday, January 23, 2025

Before animals: the evolution of life

Choanoflagellate colony stained to highlight DNA and other features (Nicole King lab)
Mono Lake’s extreme environment, characterized by high salinity and toxic substances such as arsenic and cyanide, may have driven the evolution of this distinctive species.
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California discovery may explain evolutionary arising of animals
Microscopic choanoflagellate B. monosierra
(The Brighter Side of News) Mono Lake, nestled in Northern California’s Eastern Sierra Nevada, is a haven for unique life forms [as it fills with water washing down from Yosemite National Park's alpine lakes, most of which evaporates faster than it can be replenished].

Its iconic tufa formations and thriving populations of brine shrimp (aka fly larvae) and alkali flies showcase an ecosystem adapted to the lake's hypersaline, alkaline waters.
  • PHOTO: Globular colonies of the choanoflagellate Barroeca monosierra seen under a microscope. As indicated by the 50-micron scale bar in the upper left, these colonies are at the limit of what’s visible to the naked eye (Alain Garcia De Las Bayonas, Nicole King lab, © The Brighter Side of News).
Dhamma Aboard Evolution: Agganna Sutta
Now, researchers from the University of California at Berkeley have identified a microscopic organism in this extreme environment that could illuminate the early evolution of life.

The discovery is a single-celled organism called a choanoflagellate, a group that holds special significance in the study of evolution. Although not animals themselves, choanoflagellates are the closest known living relatives of animals.

Their biology offers vital clues about the transition from single-celled to multicellular life. What sets this particular species apart is its microbiome.

Unlike other choanoflagellates, which typically consume bacteria, this species forms a stable, physical association with its bacterial partners. This makes it the simplest known organism to host a microbiome, providing researchers with an unprecedented opportunity to study how early interactions between single-celled organisms and bacteria influenced the evolution of complex life, including animals.

This could explain life.
“Very little is known about choanoflagellates, and there are interesting biological phenomena that we can only gain insight into if we understand their ecology,” says Nicole King, a professor of molecular and cell biology at UC Berkeley and an investigator for the Howard Hughes Medical Institute. More
  • Ancient tribal protectors of Mono Lake: Kucadikadi ("shrimp eaters" or "fly people"), Northern Paiute of California
The Chicken or the Egg?
I don't think, therefore I'm notRene
Which came first, the chicken or the egg? It's very simple in reality. Only in theory it's impossible to answer because it's a philosophical paradox or causality dilemma. The conundrum is a kind of logical fallacy of getting caught up in categories, terminology, and semantics, losing sight of the fact that we as onlookers are the ones creating the arbitrary labels, determining the limits of categories, and making the subjective judgments to include somethings and exclude others.
  • The dilemma stems from the observation that all chickens hatch from eggs and all chicken eggs are laid by chickens, a situation where it is not clear which of two events should be considered the cause and which should be considered the effect, to express a scenario of infinite regress, or to express the difficulty of sequencing actions where each seems to depend on others being done first.
Wittgenstein would be dismayed. The answer, of course, is the proto-chicken, a creature which is a "chicken" because it lays chicken eggs but is not a chicken because it itself was not born of such an egg. Yet, if it looks like a chicken and clucks like a chicken, it is chicken enough because it does the most important thing, which is to give birth to chickens rather than it itself being born the way "chickens" are thereafter. (The exact same evolutionary question might be asked of Homo sapiens or modern humans. Which came first, the human or the womb? If all humans are born of wombs and all human wombs are produced [only] by humans, we're in the same dilemma. (Neither is completely true, but we begin with this assumption to our detriment).

The excellent thing about this discovery by UC Berkeley, my own alma mater, is that it gets at the reality and avoids the logical trap, causality dilemma, or infinite regress logicians would be caught in. There is a transitional creature that is neither yet fully animal nor solely pre-animal because it has a stable microbiome it has partnered with. Similarly, humans born of a womb and giving birth via a womb must have been preceded by a humanoid creature who did not do both.

Where did animals like us come from? That is the question at hand. If this is how "animals" behave and get defined (born of womb and birthing others via a womb), we will trap ourselves in assumptions and the rules of logic. Once we broaden the category to include the proto-animal, or in this case the choanoflagellate with a microbiome, we can begin to see how things might have gone through an intermediary phase not allowed for, assumed, or understood by our strict logic. So hooray for the transitional creature that yet remains alive to be studied that we might understand these animal bodies we identify with as and cling to as "self."

Monday, March 4, 2024

How life on Earth began, according to science

David Nield, ScienceAlert via msn.com, 3/4/24; Skeptic Central, Wisdom Quarterly
In the beginning, the Vesicle Blob. Like it or lump it, but thou shalt not question it (ScienceAlert)
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We may finally know how the first cells on Earth formed
In the beginning, rebirth ad infinitum.
The story of how life started on Earth [called the Agganna Sutra in Buddhism and Genesis or the Garden of Eden in the Abrahamic faiths] is one that scientists are eager to learn.

Researchers may have uncovered an important detail in the plot of Chapter One: an explanation of how bubbles of fat came to form the membranes of the very first cells.

A key part of the new findings, made by a team from The Scripps Research Institute in California, is that a chemical process called phosphorylation may have happened earlier than previously thought.

This process adds groups of atoms that include phosphorus to a molecule, bringing extra functions with it -- functions that can turn spherical collections of fats called protocells into more advanced versions of themselves, able to be more versatile, stable, and chemically active.
  • Diagram of life beginning on Earth
    We howl with laughter at religion for believing in fairytales but bow in solemn obedience to the inerrant utterances of white lab coat-clad priests in their lab-temples doing their lab stuff and coming out with papers about it. The sacred word, peer reviewed by fellow priests, spins a yarn and we all say, "Well, that's the way it has to be because Science don't make no junk." The figurative and metaphorical language a visionary (rishi) like the Buddha, Mahavira, Shankara, Moses, or Mohammed might have used, hah, that's of no use to us. It's fine if we want to throw out ancient written texts for new, but to ignore that Science tries to get away with explaining the universe by saying, "If you allow us just one unexplained miracle, the Big Bang, we can explain everything after that" is pitiful. Then anything observed as happening now is used to say, "This must have been what happened the first time, originating from nothing to everything we see now with no miracle at all and no anything before the something we now live and enjoy." Go on, Science, what else happened?
These protocells are widely thought to have been vital building blocks for biochemistry more than 3.5 billion years ago, perhaps emerging from hot springs under the ocean along the way to the evolution of more complex biological structures.
  • WTH? Science claims to know how life started?
    Science observer Lloyd Pye says we have examples of microevolution but not a single example of macroevolution. Along with Michael "The Forbidden Archeologist" Cremo we are getting quite an alternative view to world history and biological origins. Yet, no one notices how Science behaves like storytellers around the campfire, making "reasonable" speculations from data like shamans spinning origin myths based on whatever is at hand to comment on? A vat of skepticism is in order and perhaps an eyeroll. Was it a good idea to trade in one set of priests for another? "God is dead" was a really good slogan if people understood what it meant, so how about we launch, "Data interpreters, get stuffed"? The first laments the loss of a guide, the latter echoes the Who's "Meet the new boss, same as the old boss" lyric. To think we're going to base our lives on what some blanketyblank opines from an ivory tower, as we grovel before the feet of impersonal objectivity and total rationality, unquestioned assumptions and men with mental defilements in charge of what we are allowed to believe? It's untenable.
Ehem, our sacred garments are now blue
"At some point, we all wonder where we came from," says chemist Ramanarayanan Krishnamurthy, from The Scripps Research Institute. "This finding helps us better understand the chemical environments of early Earth so we can uncover the origins of life and how life can evolve on early Earth."
Krishnamurthy and his colleagues hypothesized that because the process is so widespread in the body's biological functions, phosphorylation ought to have been involved in early stages of protocell formation.

Replicating conditions likely to match Earth's early days in the lab, the team combined chemicals such as fatty acids and glycerol to try and create more complex vesicles -- bubble-like structures similar to protocells that facilitate cellular processes.

With some tweaking of temperature and acidity, the researchers were able to get the chemical reactions they were looking for, proving that phosphorylation may have been at work as protocells developed in the primordial ooze.

  • Agganna Sutra and science
    The "Discourse on Beginnings" (Aggañña Sutta, DN 27) is neither satire nor parody, claims author Dr. Sugunasiri, Ph.D., as viewed by Buddhist scholars. Drawing on cosmology, Darwinism, psychology, and linguistics, this sutra paints a historically and scientifically accurate picture of Devolution and Evolution, going beyond the Big Bang. Sentient beings emerge with defilements, such as passion and craving, physically nourished with greater and greater difficulty by devolving plant life. Compatible with Western science, Dr. S, had an insight, a breakthrough in his understanding of this origin myth. What if the "beings" that first came to this earth, the âbhassara brahmas (or "supremos," a class of devas, lit. "shining ones") are understood to be PHOTONS? Why? This is true if we take the term Ã¢bhassara in its literal etymological sense of "hither-come-shining-arrow," described as "self-luminous" and "moving through the air" (akasha, "space"), "glorious" (streaming), "feeding on delight," where they remain for a very long time, "mind-made" (spontaneous), floating above and around earth before the appearance of moon and sun, before night and day. However, as accurate as this picture may be, the Buddha’s point is that knowledge of Dhamma overrides it all, explaining the title [of Dr. S's book]. More
"The vesicles were able to transition from a fatty acid environment to a phospholipid environment during our experiments, suggesting a similar chemical environment could have existed four billion years ago," says chemist Sunil Pulletikurti, from The Scripps Research Institute.

The team describes it as a "plausible pathway" for the creation of phospholipids, the more complex type of vesicle membrane. However, there's lots more study to do before we can be sure about how life came to be on Earth, [science's favorite sentence].

Looking back billions of years isn't easy, of course, but scientists continue to make discoveries...
  • [Do they, with their time machines or mystic powers? They see something now and project it back, neither understanding what they're seeing nor gaining evidence for what actually happened then.]
[And these "discoveries" are] about what happened right after Earth formed, and it all plays into our investigations into life on other planets, too.
  • [Q: Oh, are we now allowed to believe in life on other planets, according to our gatekeepers? A: "It's out there, it just doesn't come here and has never been here in any way whatsoever" is the official word. So obey and repeat this mantra until told otherwise, and never mind those pesky tardigrades on the moon.]
"It's exciting to uncover how early chemistries may have transitioned to allow for life on Earth," says biophysicist Ashok Deniz, from The Scripps Research Institute.

"Our findings also hint at a wealth of intriguing physics that may have played key functional roles along the way to modern cells."

The research has been published in Chem. Source

Sunday, November 12, 2023

Celeb-approved "orgasm shot" restored sex

Amy Reast Talker News via SWNS, Nov. 10, 2023; Ananda (Dharma Buddhist Meditation), Ashley Wells, Seth Auberon (eds.), Wisdom Quarterly
Glória Vieira, 50, "lost" her sexuality after end of 16-year marriage (Gloria Vieira via SWNS).
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British woman says celeb-approved orgasm injection made her ‘feel alive again’
If I could sell it on goop.com, I would.
The treatment has been raved about by the likes of [American actor and Goop capitalist] Gwyneth Paltrow and Kourtney Kardashian.

A woman who "lost her sexuality" after heartbreak got a celebrity-approved "orgasm shot," costing $1,400.00 per session, and said it's made her "feel alive again."

Glória Vieira, 50, felt she'd "lost" her sexuality after the end of her 16-year marriage.

It's "science." And I get to give the shots.
She said her sexuality has always been a "big part" of her identity, and she wanted to bring it back.

After some research she stumbled across research about the "orgasm shot," said to increase sensitivity and improve sex.

It is a series of injections of Platelet Rich Plasma (PRP) into the intimate areas to stimulate tissue development.

Like Stella, I got my groove back.
The treatment has been raved about by the likes of Gwyneth Paltrow, Kourtney Kardashian, and Sinitta.

Within two weeks Vieira began feeling the effects of the shot and said it was "as close as I could get to a miracle."

Vieira, an accountant based in Brighton, East Sussex, UK, said: "When my marriage ended, I wondered what I could do to make me feel like myself again. More

Sunday, September 10, 2023

Hell on Earth: World's Worst Prisons (video)

Best Documentary, 9/6/23; Seth Auberon, Ashley Wells (eds.), Wisdom Quarterly

(Best Documentary) Sept. 6, 2023: The worst prisons in the world | full documentary
  • Side with abused or abusers?
    00:00 The Worst Prisons in the World
  • 01:39 Children as young as 10 are being held in overcrowded and unsafe prison cells in Quezon City, Philippines
  • 10:23 Katrina, a European woman, is incarcerated in a prison with overcrowded cells and poor conditions, where she feels unsafe but finds solace in her cellmates
  • 19:29 In a prison, the inmates discuss the limited resources they have and the potential dangers they face, including the risk of infection from prohibited items
  • 31:29 The largest prison in Europe, Fleury-Mérogis, is struggling to control the connections between inmates and the smuggling of prohibited items
Social media: Facebook.com/BestDocumentary...

Sunday, July 23, 2023

Did AI prove our subatomic view is wrong?

PBS Space Time, June 21, 2023; CC Liu, Sheldon S. (eds.), Wisdom Quarterly

Did AI prove our proton model WRONG?
(PBS Space Time) The humble proton may seem simple enough, and they’re certainly common. People are made of cells, cells are made of molecules, molecules are made of atoms, atoms are made of electrons, protons, and neutrons, and protons are each made of three up or down quarks. Simple stuff, right? All except for that last part. Protons are actually made of many, many quarks that happen to look like three only when we look at them in a particular way. And even then, sometimes they’re made of five quarks, including the charm quark. [It's all BS and it's wrong if AI is to be believed.]

PBS member stations rely on viewers. To support a local station, go to: to.pbs.org/DonateSPACE. Sign up on Patreon to get access to the Space Time Discord: patreon.com/pbsspacetime.

Saturday, July 15, 2023

Evolution created the human cell?


Darwin's evolution or some intelligent design mechanism?
(Answers in Genesis Canada) June 30, 2023. Christian fanatic Calvin Smith takes a deep dive into the amazing kinesin protein. Unfortunately, Darwinian evolution proponents claim this protein is the result of chance, but if one takes the time to listen to the experts who have researched the topic, this video may change some minds.

More high-quality biblical content every week from

Friday, June 23, 2023

Trees have a "heartbeat," scientific study finds

Sean Cate, The Premier Daily; Pat Macpherson, Dhr. Seven (eds.), Wisdom Quarterly
Researchers discover that trees have a "heartbeat," it's just so slow we've never noticed before.
Beautiful young woman hugs a tree, enjoying nature and smiling (free stock by videvo.net)

Trees hold a special place in our hearts, as they possess a longevity that surpasses most other creatures.

These remarkable organisms can live for thousands upon thousands of years. In fact, the oldest recorded tree boasted an incredible age of over 5,000 years!

Its roots reached back to a time when Rome stood at the peak of its glory -- an inspiring testament to the longevity of trees, making them some of the oldest living beings on our planet.

We acknowledge that trees are alive, for they harness energy to sustain their existence [and ours]. Though they lack the organs found in mammals like us, trees possess their own unique set of structures that enable their survival.

But being alive, do they possess a heartbeat?

Mystery of the Heartbeat
While trees do not possess a heart in the same way humans do, the idea of them having their own rhythm and pulsation is not as far-fetched as it might seem.

A recent study conducted by András Zlinszky, Bence Molnár, and Anders S. Barfod from Hungary and Denmark has shed light on an extraordinary aspect of trees: They possess a special type of pulsation akin to a heartbeat. More

Wednesday, July 29, 2020

How your cell phone spies on you (video)

Whistleblower Edward Snowden, JRE (Joe Rogan Experience, Oct. 23, 2019); Wisdom Quarterly


Edward Snowden: How our cell phones spy
(JRE Clips) Taken from JRE #1368 with Edward Snowden, where Joe Rogan hears from American whistleblower -- who reveals what the NSA and CIA are doing to spy and throw a dragnet on Americans using cell phones and other electronic information -- in what many think is impossible because of privacy rights and civil protections. The PR campaign has made many accept it, so it may not come as a surprise what we are learning. After all, "you can't wake up someone who's only pretending to be asleep." Why wake up? Stay asleep.

Monday, December 7, 2015

Science: Humans CAN photosynthesize!

Xu C1, Zhang J, Mihai DM, Washington I. (J Cell Sci. 2014 Jan 15;127(Pt 2):388-99. doi: 10.1242/jcs.134262. Epub 2013 Nov 6.) Columbia U. Medical Center, NY, NY (ncbi.nlm.nih.gov); Dhr. Seven, CC Liu, Wisdom Quarterly via Carla Golden (carlagoldenwellness.com)
 
Light-harvesting chlorophyll pigments enable mammalian mitochondria to capture photonic energy and produce ATP.
 
ABSTRACT
Human/animal cells power miracles.
Sunlight is the most abundant energy source on this planet. However, the ability to convert sunlight into biological energy in the form of adenosine-5'-triphosphate (ATP) is thought to be limited to chlorophyll-containing chloroplasts in photosynthetic organisms. Here we show that mammalian mitochondria can also capture light and synthesize ATP when mixed with a light-capturing metabolite of chlorophyll.
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The same metabolite fed to the worm Caenorhabditis elegans leads to increase in ATP synthesis upon light exposure, along with an increase in life span. We further demonstrate the same potential to convert light into energy exists in mammals, as chlorophyll metabolites accumulate in mice, rats and swine when fed a chlorophyll-rich diet.
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Results suggest chlorophyll type molecules modulate mitochondrial ATP by catalyzing the reduction of coenzyme Q, a slow step in mitochondrial ATP synthesis. We propose that through consumption of plant chlorophyll pigments, animals, too, are able to derive energy directly from sunlight.
 
INTRODUCTION
http://jcs.biologists.org/content/call-papers-3d-cell-biologyDetermining how organisms obtain energy from the environment is fundamental to our understanding of life. In nearly all organisms, energy is stored and transported as adenosine-5′-triphosphate (ATP).

In animals, the vast majority of ATP is synthesized in the mitochondria through respiration, a catabolic process. However, plants have co-evolved endosymbiotically to produce chloroplasts, which synthesize light-absorbing chlorophyll molecules that can capture light to use as energy for ATP synthesis.

Light (photons) is the substrate of matter.
Many animals consume this light-absorbing chlorophyll through their diet. Inside the body, chlorophyll is converted into a variety of metabolites (Ferruzzi and Blakeslee, 2007; Ma and Dolphin, 1999) that retain the ability to absorb light in the visible spectrum at wavelengths that can penetrate into animal tissues.

We sought to elucidate the consequences of light absorption by these potential dietary metabolites. We show that dietary metabolites of chlorophyll can enter the circulation, are present in tissues, and can be enriched in the mitochondria.

The bottom line? Maybe we are what we eat.
When incubated with a light-capturing metabolite of chlorophyll, isolated mammalian mitochondria and animal-derived tissues, have higher concentrations of ATP when exposed to light, compared with animal tissues not mixed with the metabolite.

We demonstrate that the same metabolite increases ATP concentrations and extends the median life span of Caenorhabditis elegans, upon light exposure -- supporting the hypothesis that photonic energy capture through dietary-derived metabolites may be an important means of energy regulation in animals.

The presented data are consistent with the hypothesis that metabolites of dietary chlorophyll modulate mitochondrial ATP stores by catalyzing the reduction of coenzyme Q. These findings have implications for our understanding of aging, normal cell function, and life on earth.
 
http://jcs.biologists.org/content/call-papers-3d-cell-biology RESULTS
Light-driven ATP synthesis in isolated mammalian mitochondria To demonstrate that dietary chlorophyll metabolites can modulate ATP levels, we examined the effects of the chlorophyll metabolite pyropheophorbide-a (P-a) on ATP synthesis in isolated mouse liver mitochondria in the presence of red light... More

Tuesday, December 17, 2013

Disturbing NASA document exposed (video)

Pfc. Sandoval, Pat Macpherson, Wisdom Quarterly; Deborah Tavares, Trevor Coppola
(ADG); ADG Facebook/Twitter) Shocking firsthand evidence of war plans against Americans
 
Make funk not war (CP)
Earlier this year an alarming document was brought to the attention of Deborah Tavares. It was found on the official NASA website. It is the text of a Powerpoint presentation, a document that outlines WAR PLANS against American citizens. The plans were devised by the U.S. government, or some rogue element within our military-industrial complex. It was delivered by Chief NASA Scientist Dennis Bushnell at the Langley Center a few months before 9-11.
 
Review "The Future is Now"
This information -- exposing the purpose of chemtrails (micronized aerosol contaminants sprayed over large populations), cell towers, currency collapse, smart meters, HAARP, biological and frequency weapons, and so on -- is available so everyone can stay informed. Review the document (PDF). In this way every individual can make a decision to act on it or not. If "ignorance is bliss," that may not be everyone. More