Showing posts with label brain imaging. Show all posts
Showing posts with label brain imaging. Show all posts

Monday, December 22, 2025

Science 'films' HAPPINESS in brain


Better living through (natural) chemistry
There's a chemical in dark chocolate (real Theobroma cacao) related to happiness and good sensations. It's also present in mary-jah-wanna, which probably explains why consumers get so clingy and attached to using the herbal substance. This naturally occurring chemical is called 
anandamide. Ananda, of course, is the name of the Buddha's closest friend and monastic attendant (likely his son with Mriga from before the birth of Rahula with his wife Yasodhara (aka Bimba Devi, according to some Buddhist schools). In Sanskrit and Pali anand means "bliss, joy, rapture." The suffix amide is added: In the usual nomenclature, one adds the term "amide" to the stem of the parent acid's name. For instance, the amide derived from acetic acid is named acetamide (CH3CONH2).
Now, one might be wondering, “What on earth is anandamide, and why should I care?” Well, pull up a chair and grab a square of dark chocolate, because we’re about to embark on a flavor-filled journey into the world of neuroscience and cocoa chemistry. Anandamide, derived from the Sanskrit word ananda, meaning “bliss or joy,” is a naturally occurring compound in our brains. It’s part of the endocannabinoid system, a complex network that helps regulate various bodily functions, including mood, appetite, and pain sensation. In essence, anandamide is the brain’s very own mood-enhancing, stress-busting superhero. But how does this marvelous molecule work its magic? When anandamide binds to specific receptors in our brains, it triggers a cascade of feel-good effects. More

Buddha's Brain: Neuroscience of Happiness
Happiness is literally an inside job
, according to scientific materialism, which believes that we are nothing more than material constructs and that the miracle of consciousness is but an epiphenomenon following on the interaction of material objects like cells, chemicals, molecules, and ever smaller atom, electrons, and quarks.

Organized religion errs on the side of spiritualism, believing us to be a "soul," "spirit," or "magical subtlety." These three things are real, but they are not the self any more than consciousness is.

There is nama rupa, "name" (the instructions) and "form" (the carrying out of those instructions in the material sphere). But self (atta) is not that. How else could it be? If it not one, it has to be the other, unless it is both? It is both both and neither.

What we regard as "self" (soul, ego) is mind-and-body, but though mental and physical processes exist and are active, they do not amount to a concrete "self."

The "self" that exists is dependent, temporary, ephemeral subject to Three Characteristics of All Conditioned Things: they are impermanent, incapable of satiating/fulfilling, and are impersonal.

This last characteristic is the one that is impossible to believe, but it is the key to awakening/enlightenment in the Buddha's teaching.

We can see that all things are impermanent, in flux, constantly changing, undependable. We can see that we have never been fulfilled for long; we experience great pleasure but remain hungry, in many cases becoming more hungry for newer and better pleasures.

IF THERE IS NO SELF, WHAT IS THERE THEN? The Buddha answered this question in terms of Dependent Origination (paticca-samuppāda). And it is on account of not seeing this, not grasping, not penetrating this that we have wandered so long in this painful samsara.

Will we fall under the spell of scient-ism, run to religion for shelter, or begin to see what the Buddha was getting at when he encouraged us to strive for calm and liberating-insight?

"Science can prove what it says." Can it? It redefines "happiness" as an endorphin then shows a peptide "walking," and viola, nonmaterialistic Buddhism is wrong? That's how it might seem, but it is not the case. We must look more deeply. Science fails us. And coming and seeing and investigating what the Buddha taught liberates us. Try it.

Buddha's Brain: The Practical Neuroscience of Happiness, Love, and Wisdom
Preface by Jack Kornfield
(Paperback) Authors Dr. Rick Hanson Ph.D. and Dr. Richard Mendius, MD (with preface by Jack Kornfield and foreword by Dr. Daniel J. Siegel, MD) have 4.7 out of 5 stars (with 2,019 reviews).

Change your brain, change your life with this essential classic from New York Times bestselling author Dr. Rick Hanson—now celebrating 15 years in print with more than 500,000 copies sold.

Great teachers like the historical Buddha, Jesus, Moses, Mohammed, and Gandhi were all born with brains built essentially like everyone else’s—and then they changed their brains in ways that changed the world.

Neuroscience now reveals how the flow of thoughts actually sculpts the brain. More and more, we are learning that it’s possible to strengthen positive brain states.

By combining breakthroughs in science with insights from thousands of years of mindfulness practice, we too can shape our own “Buddha’s Brain” for greater happiness, love, and wisdom. 

Buddha’s Brain draws on evidence-based neuroscience to show readers how to stimulate their brains for
  • more fulfilling relationships,
  • a deeper spiritual life, and
  • a greater sense of inner confidence and self-worth.
Using guided meditations and mindfulness exercises, learn how to activate the brain states of calm, joy, and compassion instead of worry, sorrow, and anger.

Most importantly, anyone who implements these practices will foster positive psychological growth that will literally change the way life is lived day-to-day.

This book provides an essential intersection of psychology, neurology, and contemplative practice. It’s filled with practical tools and skills useful every day to tap into the unused potential of the brain and rewire it over time for greater well-being. More

Tuesday, July 25, 2023

The brain's perception deception (NOVA)

NOVA PBS Official, May 17, 2023; CC Liu, Sheldon S. (eds.), Wisdom Quarterly

Your Brain: Perception Deception | full documentary | NOVA | PBS
Buddha's Brain (Dr. Rick Hanson, Ph.D.)
(NOVA PBS Official) Is what we see real? Join neuroscientist Heather Berlin on a quest to understand how our brain shapes our reality, and why we can’t always trust what you perceive.

In the first hour of this two-part series, learn what the latest research shows about how our brain processes and shapes the world around us, and discover the surprising tricks and shortcuts our brain takes to help us survive.

CHAPTERS
  • 00:00 Introduction
  • 03:59 The Science of Optical Illusions and Blind Spots
  • 13:48 Is the Dress Blue and Black or White and Gold?
  • 21:06 Yanny or Laurel? Auditory Illusions
  • 24:46 Is Pain an Illusion?
  • 30:28 What is Consciousness? Blind Spots and Babies
  • 41:35 How is Consciousness Measured?
  • 45:32 How the Brain Affects Memories
  • 50:14 Conclusion
Official website: to.pbs.org/3Ic9dRS | #novapbs
© 2023 WGBH Educational Foundation. All rights reserved.  This program was produced by GBH, which is solely responsible for its content. This program is made possible by viewers like us. Support our local PBS station: pbs.org/donate. Enjoy full episodes of favorite PBS shows anytime, anywhere with the free PBS App: to.pbs.org/2QbtzhR. Stay up to date on the latest science discoveries, full episodes, articles, videos, and more by signing up for NOVA's newsletter.

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Wednesday, April 3, 2013

Obama's Deadly Brain Mapping Money

Pat Macpherson, Pfc. Sandoval, Wisdom Quarterly; Alex Cohen, A. Martinez, "Take Two"
Human brain (Mauricio Lima/AFP/Getty Images)
 
B.S. O'lama: Big plan. You'll see.
Just when he sounded like he was doing something good and useful, the truth comes out. The Nobel Peace Laureate President is making sure at least half the research money goes to one military use: DARPA (the Defense Advanced Research Projects Agency for secret military weapons development at www.darpa.mil). What do they do? They make the deadliest most secretive weapons on Earth.

(Take Two) One of the greatest mysteries of science is right inside our skulls: the human brain.
 
Killing is our business, and business is good
Yesterday President Obama announced an initiative to help map our minds. [Will the government be reading them next and fulfilling Orwell's dystopian dream of criminalizing "thought crimes"? Why not? If it means fewer civil liberties and greater military-industrial control it will fit right into the fifth (G.H.B. x 1, G.W.B. x 2, B.S.O. x 2 = 5)  Bush administration's Brave New World Order.] 
 
Yer gonna make me so much money!
The President has pledged to put $100 million [in addition to the countless billions of unaudited funds] toward developing a map that would do for the brain what the human genome project did for DNA. [Science means using knowledge to control and manipulate reality for the profit of private corporations which externalizes costs and internalizing profits like WalMart.] Here to talk the new "Brain Initiative" is Dr. William Newsome of Stanford University on SCPR.org's TAKE TWO (LISTEN).

Really, a Brain Initiative?
(Letters and Politics, KPFA, Berkeley, April 3, 2013, 10:00 am)
Host Mitch Jeserich discusses mapping the brain with University of California Berkeley neuroscientist John Ngai and John Julius Norwich, author of Absolute Monarchs. Together they take a much more in-depth look at what is really motivating the current administration and where the money will be funneled in spite of the mainstream media's cheer leading. More

Tuesday, September 27, 2011

Scientists translate dreams into YouTube videos

Gallant Labs UC Berkeley, Wisdom Quarterly, The Consumerist
() Left clip: segment of Hollywood movie trailer subject viewed while in fMRI machine. Right clip: reconstruction of segment from brain activity measured using functional magnetic resonance imaging.

Translating brain activity into YouTube videos

BERKELEY, California - Science is getting closer to letting people see through the eyes of others. UC Berkeley scientists have designed a way to read brain activity and reconstruct YouTube videos.... broadcasting the mental images people create, meaning you could soon watch others' dreams.
  • It would be amazing to hook up Buddhist saints (Noble Ones) or at least monastics and asking them to meditate or "see" nirvana. We know those who have seen it exist.
(Meggito/Flickr)

The Gallant Lab at UC Berkeley had people watch videos while hooked up to an MRI machine, then matched the data and brain activity to shapes, movement, and colors. The computer model the researchers created blurry, dreamlike images. More
Procedure
1. Record brain activity while subject views hours of movie trailers.
2. Build dictionaries (regression model) to translate between shapes, edges, and motion in these movies and measured brain activity. A separate dictionary is constructed for each of several thousand points in the brain at which brain activity was measured.
3. Record brain activity to a new set of movie trailers that will be used to test the quality of the dictionaries and reconstructions.
4. Build a random library of approximately 18,000,000 seconds of video downloaded at random from YouTube (that have no overlap with the movies subjects saw in the magnet).
5. Put each of these clips through the dictionaries to generate predictions of brain activity.
6. Select the 100 clips whose predicted activity is most similar to the observed brain activity.
7. Average those clips together. This is the reconstruction.

Saturday, May 14, 2011

"Mind-reading" experiment highlights brain

"Mind-reading" experiment highlights how brain records emories
(ScienceDaily) It may be possible to "read" a person's memories just by looking at brain activity, according to research carried out by Wellcome Trust scientists.

In a study published in the journal Current Biology they show that our memories are recorded in regular patterns, a finding that challenges current scientific thinking.

Demis Hassabis and Professor Eleanor Maguire at the Wellcome Trust Centre for Neuroimaging at UCL (University College London) have previously studied the role of a small area of the brain known as the hippocampus, which is crucial for navigation, memory recall, and imagining future events.

Now the researchers have shown how the hippocampus records memory.

When we move around, nerve cells (neurons) known as "place cells" located in the hippocampus, activate to tell us where we are.

Hassabis, Maguire, and colleagues used a functional MRI (fMRI) scanner, which measures changes in blood flow within the brain, to examine the activity of these places cells as a volunteer navigated around a virtual reality environment. The data were then analyzed by a computer algorithm developed by Demis Hassabis.

"We asked whether we could see any interesting patterns in the neural activity that could tell us what the participants were thinking, or in this case where they were," explains Professor Maguire, a Wellcome Trust Senior Research Fellow.

"Surprisingly, just by looking at the brain data we could predict exactly where they were in the virtual reality environment. In other words, we could 'read' their spatial memories." More

Psychologists have found that thought patterns used to recall the past and imagine the future are strikingly similar. Using functional magnetic...
Mind and Brain
Strange Science (Reference)

Thursday, July 31, 2008

Unknown Pain Facts: Dukkha


Pain The International Association for the Study of Pain (IASP) Committee for Taxonomy defines pain as "an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage...pain is always subjective. Each individual learns the application of the word through experiences related to injury in early life" (Merskey, 1994). wittgensteinforum.wordpress.com
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Pain forces an estimated 36 million U.S. residents to miss work every year and results in roughly 70 million doctor visits. Studies find that exercise is in many cases one of the best remedies for chronic pain.
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5 Painful Facts You Need to Know
By Robert Roy Britt (LiveScience, July 25, 2008)

First off, let's set the record straight: Pain is normal. About 75 million U.S. residents endure chronic or recurrent pain. Migraines plague 25 million of us. One in six suffer arthritis.

The global pain industry peddles more than $50 billion in drugs a year. Yet for chronic pain sufferers, over-the-counter pills are typically little help, while morphine and other narcotics can be addictive sedatives.

An overview study published last month in the Journal of General Internal Medicine looked at multiple studies of pain and found "researchers don't yet know how to determine which [treatment] is best for individual patients." From studies of drugs to surgeries and alternative medicines, "We have found that there are huge gaps in our knowledge base," said Dr. Matthew J. Bair, assistant professor of medicine at the Indiana University School of Medicine.

So what is pain and why do so many suffer so long?
Pain is felt when electrical signals are sent from nerve endings to your brain, which in turn can release painkillers called endorphins and generate reactions that range from instant and physical to long-term and emotional. Beyond that, scientific understanding gets painfully fuzzy. Here's what's known:

1. Scientist don't understand pain
When you're in pain, you know it. But if scientists could fully grasp how pain works and why, they might be able to help you more. The American Academy of Pain Medicine defines pain as "an unpleasant sensation and emotional response to that sensation." Some pain is the result of an obvious injury. Other times, it is caused by damaged nerves that are not so easy to pinpoint. "Pain is complex and defies our ability to establish a clear definition," says Kathryn Weiner, director of the American Academy of Pain Management. "Pain is far more than neural transmission and sensory transduction. Pain is a complex mixture of emotions, culture, experience, spirit and sensation."

2. Chronic pain shrinks brains
If you have chronic pain, you know how demoralizing and debilitating it can be, physically and mentally. It can prevent you from doing things and make you irritable for reasons nobody else understands. But that's only half the story. People with chronic backaches have brains as much as 11 percent smaller than those of non-sufferers, scientists reported in 2004. They don't know why. "It is possible it's just the stress of having to live with the condition," said study leader A. Vania Apkarian of Northwestern University. "The neurons become overactive or tired of the activity."

3. Migraines and sex go together
It may not eliminate the phrase "Not tonight, honey ..." but a 2006 study found that migraine sufferers had levels of sexual desire 20 percent higher than those suffering from tension headaches. The finding suggests sexual desire and migraines might be influenced by the same brain chemical, and getting a better handle on the link could lead to better treatments, at least for the pain portion of the equation.

4. Women feel more pain
Any man who has watched a woman having a baby without using drugs would swear that women can tolerate anything. But the truth is, guys, it hurts more than you can imagine. Women have more nerve receptors than men. As an example, women have 34 nerve fibers per square centimeter of facial skin, while men average just 17. And in a 2005 study, women were found to report more pain throughout their lifetimes and, compared to men, they feel pain in more areas of their body and for longer durations.

5. Some animals don't feel our pain
Animal research could offer clues to eventually relieve human suffering. Take the naked mole rat, a hairless and nearly blind subterranean creature. A study this year found it feels neither the pain of acid nor the sting of chili peppers. If researchers can figure out why, they might be on the road to new sorts of painkilling therapies for humans. In 2006, scientists found a pathway for the transmission of chronic pain in rats that they hope will translate into better understanding of human chronic pain. Lobsters feel no pain, even when boiled, scientists said in a 2005 report that is just one more salvo in a long-running debate.
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Video-link. Kishore took part in a meditation/anxiety study in February. The study focused on emotion processing and anxiety and how these might change with mindfulness-based stress reduction or cognitive-behavioral therapy (i.e., how meditation affects anxiety). The process was similar to the one shown in this video (courtesy Science Friday)
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What you can do
Meanwhile, exercise is a useful remedy for many types of chronic pain. In an Italian study detailed in the May issue of the journal Cephalalgia, office workers did relaxation and posture exercises every two to three hours. Over an eight-month period, they kept diaries, which were then compared to those of a control group that did not change habits. In the end, the group that exercised reported that headaches and neck and shoulder pain decreased by more than 40 per cent, and their use of painkillers was cut in half.

"Physical activity is actually a natural pain reliever for most people suffering from arthritis," concludes another study published in the Arthritis Care and Research journal in April. "Even minor lifestyle changes like taking a 10-minute walk three times a day can reduce the impact of arthritis on a person's daily activities and help to prevent developing more painful arthritis," said Dr. Patience White, chief public health officer of the Arthritis Foundation. "Physical activity can actually reduce pain naturally and decrease dependence on pain medications."

alphachimp.com
A Buddhist Point of View
Dukkha (the range of pain) definition: dukkhatā (abstract noun from dukkha): "the state of suffering," painfulness, unpleasantness, the unsatisfactoriness of existence. "There are three kinds of suffering:
  • (1) suffering as pain (dukkha-dukkhatā),
  • (2) the suffering inherent in the formations (saṅkhāra-dukkhatā),
  • (3) the suffering in change (vipariṇāma-dukkhatā)" (S. XLV, 165; D. 33).

(1) is the bodily or mental feeling of pain as actual]y felt.

(2) refers to the oppressive nature of all formations of existence (i.e., all conditioned phenomena), due to their continual arising and passing away; this includes also experiences associated with neutral feeling.

(3) refers to bodily and mental pleasant feelings, "because they are the cause for the arising of pain when they change" (Path of Purification XIV, 34f).

Nirvana: (verb) the end of all suffering; lit. "to blow out," "extinction" [of suffering] (nir + √vā, to cease blowing, to become extinguished); according to the commentaries, "freedom from desire (nir + vana). Nirvana constitutes the highest and ultimate goal of all Buddhist aspirations...the ultimate and absolute deliverance from all future rebirth, old age, disease, and death, from all suffering and misery.

Abhidharma (Buddhist Psychology)
"Feeling" is one of the five basic supports for the continued existence of a being. Through watching various aspects of it, a relationship can be seen between the sense pentad and the Factors of Absorption (jhananga). Through the analysis of this relationship, it can be seen how watching "feeling" may lead to the development of one's being and understanding.

The basis of being
Two parallel processes -- nama (mentality) and rupa (materiality) support each other continuously in existence. When an active regenerative energy from an action is carried over as vinnana (consciousness) and contacts a material group ready for support, rebirth occurs. This can be the rebirth of a human being, a deva, a habit, a process, or a conscious experience.

The material process manifests four qualities that interrelate in all forms:
  • solidity or mass which has hardness or softness
  • cohesion which holds together through flowing
  • warmth which allows change through maturing
  • air which gives support to structure through distending
Matter under these four aspects is combined with life energy when the matter is related to life processes such as that forming the six sense bases (eye, ear, nose, tongue, body, and mind).

Matter also forms objects for the first five sense bases. The sixth base can have matter as well as derived material qualities (masculinity, femininity, verbal, and bodily expression, etc.), and non-material objects such as concepts, mental states, and nirvana as its object.

The contact between one of these sense bases and an appropriate object produces a sense consciousness and leads to the arising of the nama aspect of being.

Nama (mentality), like rupa (materiality), is the coexistence of four qualities. In the case of nama, these are
  • vedana (feeling)
  • sanna (cognition)
  • sankhara (mental formations)
  • vinnana (conscious awareness)

These four occur as the first set of factors with all forms of consciousness that arise.

Vedana is feeling, the initial "taste" or essence of an aspect of the object. All contacts, sensory or cognizable (mental), feed vedana. The quality of the food depends on the degree of agreeableness of the object and on the state of the receptive base at the moment of contact.

Sanna resolves, cognizes, and discerns. It perceives the nature of the object without reacting to it. It is an impression of the awareness of an object so that the object may be re-cognized when necessary.

Sankhara is the collection of the coefficients of consciousness that give consciousness activity. Cetana, or intention, [is a characteristic] sankhara, which is like active thought, since it coordinates factors that are present at the time. Purpose, or intention, in relation to the object then arises. It feeds the mind and gives impetus for the wish to have, to know, or to think, that is, the determination to continue being.

Vinnana is that aspect of conscious experience that is actively "minding." It watches and categorizes with vitality, thus feeding the dependence on categories already formed. It is that which carries forward "categorized volition" to condition the subsequent state of being.

This should be distinguished from citta [mind/heart], another aspect of conscious experience, which is based on the heart. Here an emotional and intuitive reviewing and understanding of the object occurs. This is the result of an examination of the object which is wider and so intensifies the knowledge of it.

Contacts allow objects to be experienced from these existing four aspects of nama. Together with contact this group is sometimes termed the sense pentad, which occurs in all spheres of life, providing an apparently "continuous" basis for conscious experiences....Analysis of feeling
  • Read more (essay: sense function and the absorptions)
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