End vicious circle of negative habits 💀

(Moon Mind Temple) Buddhist teachings that end the vicious circle of negative habits | Zen stories for deep peace (Thich Nhat Hanh)

The 'magic cactus' flower: sacred peyote

(Forgotten Crops) Why does this entheogenic cactus cause magical "hallucinations"?

Higher levels of consciousness

Ancient Egyptians took psychedelic blue lily

• Peyote
• Blue water lily/lotus (Nymphaea nouchali)
• Entheogen
• Carlos Castaneda
• Psychoactive drug
• Psychedelic experience
• Shamanic "sacrament"
• Banned by Spanish Empire
• Altered state of consciousness

DMT dangers, risks: Trickster elf entities

• Why 100% of scientists agree that DMT experiences and entities are NOT hallucinations 🤯

Did Carl Jung figure it out?

(OurTimelessWisdom) Jung theory explains DMT entities: Terence McKenna

(OurTimelessWisdom) DMT: Risk vs. Reward: the cost of seeing what we are not ready to see:

Illustrated Field Guide to DMT Entities: Machine Elves,
Tricksters, Teachers, Other Interdimensional Beings

• Animated Entities:) on Reddit: r/DMT

Rupert Sheldrake on elves, visions

(The Institute of Art and Ideas) Why do we see elves on DMT? | Rupert

Sheldrake (on morphic resonance, cultural collective memory)

DMT entity mystery breaks science: What are they? | Dr. Andrew Gallimore

The DMT entity mystery that breaks science: What are these beings?

(OurTimelessWisdom) The DMT Entity Mystery That Breaks Science: What Are These Beings? 👁️

DMT entity Machine Elf (Tricky Woo)

If these beings are real — science is over. Every time someone smokes DMT, that person meets the same thing: "machine elves," DMT entities. What are they? They are hyperdimensional beings who laugh, welcome you, trick you, and teach you. Who are they? And why do they act like they’ve known visitors forever?

🔍 This video rewires how we understand consciousness, intelligence, and the mind. In this rare, mind-bending interview, Dr. Andrew Gallimore — computational neurobiologist and the author of Alien Information Theory — breaks down the DMT entity mystery in full.

This is not fringe speculation. It is a direct challenge to neuroscience, physics, and the very Jungian idea of a "collective unconscious."

Andrew R Gallimore (Amazon)

🧩 DR. GALLIMORE EXPLORES:

🧠 Why the “just hallucinations” theory fails

📡 How the brain may be receiving data from “elsewhere”

👁️ Why everyone sees the same machine elves during DMT trips

📖 The earliest reports in DMT science, echoing Terence McKenna’s lectures

🃏 Their bizarre behavior -- part guide, part trickster

🔁 Why they say: “Welcome back! We’ve missed you!”

🧪 How to use DMT as a consciousness technology — not a drug

🌀 Why even Carl Jung’s archetypes might not go far enough to explain what’s happening

👇 To the question asked, “Why do we all see machine elves on DMT?” — this is the video that finally confronts it.

⏱️ CHAPTERS AND TIMESTAMPS

0:00 – The question Dr. Gallimore has wrestled with for 20 years

0:50 – Why hallucination theory collapses under scrutiny

1:36 – Brain as a receiver? A McKenna-style cosmic broadcast?

2:22 – Collective reports: same entities, same architecture

3:05 – First DMT entities documented (Szára, 1950s)

3:48 – Trickster intelligence and language-like behavior

4:33 – A lost home? The archetypal return motif

5:12 – “Welcome back…we’ve been watching.”

6:00 – DMT + technology = stable channel

6:49 – Dr. Gallimore’s plan echoes McKenna’s long-shot vision

7:35 – Beyond Jung, beyond hallucination: the unknown Other

💡 LEARN

• Why Dr. Gallimore's DMT interview challenges scientific materialism
• How these beings behave more like psycho-spiritual archetypes or alien intelligences
• How this experience echoes Jung’s individuation process — but in hyperspace
• Why this may be the beginning of a DMT technology consciousness study
• Where McKenna’s “language of the unconscious” meets 21st-century neuroscience

🧠 WHO IS DR. GALLIMORE?

Alien Information Theory

Dr. Andrew Gallimore is a computational neurobiologist, chemist, and author of Alien Information Theory. He has spent over 20 years studying how psychedelic (entheogenic) experiences — especially on DMT — interface with the structure of our reality, the unconscious mind, and the possible existence of non-human intelligences.

He is considered one of today’s leading experts on DMT, altered states, and the neuroscience of visionary experience.

It's plan A until Plan A works, until I die! #surreal

🎯 Subscribe for more videos unpacking the mind-bending intersection of Jung, McKenna, psychedelics, and deep consciousness science.

Forever Jung Carl Jung Inspirational Quote Kiss Cut Sticker Sheet - Multiple Sizes Available ourtimelesswisdom-shop.fourthwall.com/products... Forever Jung Carl Jung Inspirational Quote Coffee Mug - Available in 11oz and 15oz - Unique Psychology Gift ourtimelesswisdom-shop.fourthwall.com/products...

• OurTimelessWisdom, June 29, 2025 (✪ Members first on June 28, 2025); Rupert Sheldrake; Pat Macpherson, Dhr. Seven, Ananda (Dharma Buddhist Meditation), Wisdom Quarterly

Consciousness: Vedas right, science finds

(Cosmos Kolo) Nobel Laureate just proved what the Vedas [India's ancient "Knowledge Books"] said 3,000 and more years ago.

• Roger Penrose, author of The Emperor's New Mind, Shadows of the Mind, The Large, the Small and the Human Mind, The Road to Reality
• Anesthesiologist Stuart Hameroff
• The Lancet
• Dutch cardiologist Pim van Lommel
• SCIENCE ILLUSTRATED; They Look Alike, but There's a Little Matter of Size - The New York Times (physicist Mark Miller, Brandeis U) Aug. 15, 2006... Mark Miller, a doctoral student at Brandeis University, is researching how particular types of neurons in the brain are connected to one another...
• Ramana Maharshi Hindu sadhu, great rishi ("seer")

Hinduism's view is wrong in Buddhism

(One Timeless Witness) Consciousness is not what you think: Ramana Maharishi's three step answer

Science: Psychology of GenX Metalheads

(Loudwire) Beavis & Butt-Head's worst takes on music (MTV)

(Frank Talk After 50) The psychology of Gen X metalheads: What science found

• Generation X
• Tipper Gore (Al Gore's prude wife)
• Parents Music Resource Center
• Moral panic

What was the PMRC?

This 'l save our kids from capitalist exploitation

The Parents Music Resource Center (PMRC) was a bipartisan U.S. government committee formed in 1985 [1] with the stated goal of "increasing parental control over children's access to music deemed to have violent, drug-related, or sexual themes."

The committee's work led to the widespread adoption of the Parental Advisory sticker. The PMRC was known for its prejudicial targeting of heavy metal music, which drew opposition and criticism [2].

Beavis & Butt-Head ROAST some metal

(Loudwire) Top 10 MTV's Beavis & Butt-Head metal ROASTS

Tipper and Al Gore get married in 1970

On political and religious grounds, the committee was supported by American Protestant televangelists, Reaganites, and the larger Christian evangelical movement, who accused hard rock and heavy metal music of harboring Satanic and occult related themes.

The committee was founded by four women known as the "Washington Wives"—a reference to their husbands' connections with the government power elite in the Washington, D.C. area.

Those female founders of the PMRC are Tipper Gore, wife of Senator and later Vice President Al Gore... More

(RetroVibe) Funny songs every Gen X kid grew up hearing

Who cares what B&B think?

(Rock N' Roll True Stories) White Zombie was flopping...

then two losers on MTV said the band didn't suck

If there's no self, whose NDE is it?

(Buddha's Wisdom) NO-SELF vs. NDEs: Buddhism's strangest question about death

• Near-death experience (NDE)
• Dr. Raymond Moody wrote Life After Life: A Groundbreaking Exploration of Near-Death Experiences and the Transformative Insights into the Afterlife, Backed by Scientific Study and Personal Testimonies
• Dr. Ian Stevenson
• Dr. Elisabeth Kübler-Ross: stages of human death
• Dr. Helen Wambach does early science in Reliving Past Lives: The Evidence Under Hypnosis
• If there is no permanent "self," what is there then?
• Saṃsāra is not Nirvana, but is to say so helpful?
• What is Liberation (Moksha) but Awakening to the Truth that this was all a Dream (Maya)?
• Death (marana) is death because it is immediately followed by rebirth; there is no space in between, as the Bardo is misunderstood to be, because it will not be another human rebirth next
• At the instant of death, in that submoment, what was a human life is lost, the impersonal process of consciousness relinks and rearises according to karma in a new form. It is neither a new existence nor the same as the one before, and this is confusing. Identity clings. But just as it was impersonal before, it is impersonal still, and the process (patisandhi in samsara) rolls on. Samsara is the "continued wandering on" and its detailed process the Buddha made known in the Abhidhamma, how cittas (mind moments) and impuslions (javanas) produce their results (vipaka and phala), and a "being" (which is really always a becoming) is unaware and just carried on...

The 6th sense humans had before 1850

(Rewired Era) The sixth sense human all had before 1850: They bred it out and no one knows why but indigenous aboriginal "wayfinders" can still know where they are and where they're going

Mind cannot be seen, so where is it?

(Buddhism Podcast) The mind cannot be seen, so where is it? | Buddhist Wisdom

But what is aware that it is aware?

There is a mind-door, greenish in hue, near the heart. This heart-mind seems to be the physical base of consciousness, not the brain in the cranium. When meditating, attention can be adverted to the area around the heart. There there is a mirror reflecting experience, consciousness, awareness. If the "mind" were in the brain or the head, it seems attention would be placed there to find it. But it is very much down closer to what in the West we refer to as the seat of our emotions. The Buddha did not specify a physical base for vijñāna (consciousness) or manas (in Early Buddhism). However, he seems to have been well aware of the practical application of locating this base for the sake of realizing the ultimate nature of mind-and-matter (nama-rupa), ultimate mind (a stream of cittas) and ultimate materiality (a stream of kalapas). But this is for advanced practitioners of Buddhist meditation rather than philosophers and speculators. For those, perhaps Zen no-mind would be better or the compelling mind-only (Yogachara) view.

• Buddhism Podcast (video); text by Dhr. Seven, Ananda (Dharma Buddhist Meditation), Wisdom Quarterly

World Brain Day: the 'Buddha's Brain'

• 6 things to do when waking up for better cognitive function, recommended by neurologists
• WORLD BRAIN DAY - July 22, 2025 - National Today

Buddha's Brain: The Practical Neuroscience of Happiness, Love & Wisdom is an Audible audiobook (unabridged) by Dr. Rick Hanson, PhD. He is the author and narrator and has 4.7 out of 5 stars with 1,984 ratings.

Change your brain, change your life with this essential classic from New York Times bestselling author Dr. Hanson—now celebrating 15 years in print with more than 500,000 copies sold.

Great teachers like the Buddha, Jesus, Moses, Mohammed, and Gandhi were all born with brains built essentially like anyone else’s—and then they changed their brains in ways that changed the world.

Neuroscience now reveals how the flow of thoughts actually sculpts the brain. More and more, we are learning that it’s possible to strengthen positive brain states. By combining breakthroughs in science with insights from thousands of years of mindfulness (sati) practice, we too can shape our own “Buddha’s Brain” for greater happiness, love, and wisdom.

Buddha’s Brain draws on evidence-based neuroscience to show how to stimulate our brain for more fulfilling relationships, a deeper spiritual life, and a greater sense of inner confidence and self-worth.

Using guided meditations and mindfulness exercises, readers learn how to activate the brain states of calm, joy, and compassion instead of worry, sorrow, and anger. Most importantly, they will foster positive psychological growth that will literally change the way we live our day-to-day life.

This book provides an essential intersection of psychology, neurology, and contemplative practice, and is filled with practical tools and skills that anyone can use every day to tap into the unused potential of the brain and rewire it over time for greater well-being.

PLEASE NOTE: Purchase of this title is accompanied by a PDF in the Audible Library along with the audio. More: Buddha's Brain: The Practical Neuroscience of Happiness, Love & Wisdom by Dr. Rick Hanson, PhD, and Daniel J. Siegel, MD, with foreword by Dr. Richard Mendius, MD and contributor Jack Kornfield for preface (Brilliance Audio)

FIGHTING, anger, self-talk, emotions

Sir, please don't come at us in anger, please.

Never be angry: How to stay calm in every situation

(ThinkZone) Attia & Huberman. Dr. Andrew Huberman is a renowned neuroscientist and professor in the Department of Neurobiology at Stanford University School of Medicine. He has made significant contributions to the field of neuroscience through his research on brain plasticity, visual system development, and the mechanisms underlying various neurological disorders. Dr. Peter Attia is a prominent figure in the fields of longevity, health, and performance optimization. He is a physician, researcher, and speaker who focuses on promoting a deeper understanding of human health and well-being.

The Monster's idol Mike Tyson

Prison homosexuality exposed by bi Tyson

Who is Naoya "The Monster" Inoue?

The Pretty Boy Floyd of the ring

Naoya Inoue (井上 尚弥), a professional boxer, was born on April 10, 1993. He has held multiple world championships in four weight classes. He is one of only three male boxers in history (along with Terence Crawford and Oleksandr Usyk) to become the undisputed champion in two weight classes in the "four-belt era," becoming the second to do so [3, 4]. Nicknamed "The Monster" (怪物 Kaibutsu), he is known for his exceptional punching power, possessing a knockout-to-win percentage of 90%. More

• Never insult Naoya Inoue or this is what happens (brutal KO)
• Bully ANGERED Naoya Inoue and regretted it badly
• Naoya Inoue vs. Gervonta Davis: most insane fight ever

"Signal To Noise (CC-BY) by Scott Buckley" is under a Creative Commons (cc-by) license. Music promoted by BreakingCopyright: • 🕰️ Mystery Music (No Copyright) - "Signal..."

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• Naoya Inoue; Attia and Huberman, ThinkZone, July 1, 2024; Pfc. Sandoval, CC Liu, Dhr. Seven (eds.), Wisdom Quarterly

Where does consciousness GO after death?

Pinocchio Day: Pineal Gland Eye

I want to be a real person. Mind-blowing truth

"Pinocchio The PINEAL GLAND"

Wait, it's a real day? - Of course it is!

If Italian readers already understand, it's news to the rest of us. Are English speakers ready to understand? You will change.

The divine eye in Buddhism, the dibba cakkhu, is the third eye around the forehead, transcendent vision, the ability to "see" beyond the sight of our human eyes, perhaps rooted deep in the brain where another eye (replete with rods and cones) resides in the complete dark. What subtle waves, what broad spectrum photons, what light source is it responding to?

(daily MOTIVATION) Pinocchio the Pineal Gland Eye Boy. Subscribe to Santos Bonacci on YouTube at MrAstrotheology for more works on syncretism: @mrastrotheology 

Secrets of pineal gland: scientific proof

(i24NEWS English) The Secrets of Pineal Gland Scientific Proof

• #PinealGland #Pinocchio; daily MOTIVATION, Aug. 16, 2023; i24NEWS English, The Secrets; Pat Macpherson and Dhr. Seven (eds.), Wisdom Quarterly

Dalai Lama: What is it that reincarnates?

We have been trying to tell everyone. Emptiness (sunyata) means "things are impersonal." It is a mindboggling concept, not to be fathomed by mere reasoning. The Buddha was not Descartes sitting around thinking. He sat cleaning his mind through samadhi then systematically investigated the four scaffolds or foundations of what to be mindful of: those four things assumed to be self: form, feeling, perception, consciousness. He mindfully investigated this body, feelings, mind, and mind-objects.

If not who, WHAT is it that reincarnates? ♡ Excerpts from Dalai Lama and neuroscientists @ Mind and Life

(Global Well-Being) 🧡 Support channel by donating on PayPal: paypal.me/WhatWouldLoveDoNow Thanks! 🧡 In case this channel gets shut down, please subscribe to new channel: @compassionmatters. Thanks! If His Holiness gets replaced, support the new "Dalai Lama" (No. 15) at dalailama.com. Thanks! If you die, I mean pass away and are reborn, where do you want to meet or where will you be leaving your A.I. avatar version? you.com? Let us know. Thanks! #GlobalWellBeing

Listen to H.H. The 14th Dalai Lama and some of the leading neuroscientists of 2016 as they talk about and consider what is "subtle mind" and what it is that reincarnates.

"New theories in neuroscience suggest consciousness is an intrinsic property of everything, just like gravity. That development opens a world of opportunity for collaboration between Buddhists and neuroscientists." - Sam Littlefair, associate digital editor of Lion's Roar, April 1, 2016

lionsroar.com/christof-koc...

"The Buddha taught that sentience [feeling, consciousness, sensitivity] is everywhere at varying levels and that humans should have compassion for all sentient beings." - H.H. The Dalai Lama

"By resting his or her mind and contemplating it, a meditator can develop an understanding of the nature of mind and how it relates to everything else." - Traleg Rinpoche

Lion's Roar: Buddhist Wisdom for our Time - Magazine lionsroar.com...

Mind and Life Institute: Home: mindandlife.org Mind and Life Institute - Wikipedia en.wikipedia.org/wiki/Mind_an... The Mind and Life Institute | Facebook / mindandlife Mind & Life Institute - YouTube / mindandlifeinstitute

"May we all be happy. May we all be well. May we all be safe." - The Buddha (on metta)

Please help support channel simply by using this link when shopping on Amazon ♡ http://amzn.to/2r8Laxo ♡ Get 2 Free Audiobooks With A 30 Day Free Audible Trial On Amazon ♡ http://amzn.to/2pS0aOn ♡ Amazon's top selling gift items for him or her. ♡ http://amzn.to/2r8Laxo ♡ GLOBAL WELL-BEING: May we all learn to live together in peace and harmony with each other, ourselves, the earth and all that lives throughout time and space. TWITTER: Greater Global Well-Being Through Greater Awareness ♡ As always, Love Is The Answer ♡ That and enjoying a few good books, videos, guided meditations and more ♡ / abidemindfully 

"Use your voice for kindness, your ears for compassion, your hands for charity, your mind for truth, and your heart for love." - Global Well Being

♡ ♡ ♡ ♡ ♡ ♡ ♡ ♡ ♡ ♡

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♡ ♡ ♡ ♡ ♡ ♡ ♡ ♡ ♡

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“It has become almost impossible to say, ‘I don’t care about future generations,’ ‘I don’t care about poverty in the midst of plenty’ and ‘I don’t care if there are 200 million climate refugees in 2030. Altruism should not be relegated to the realm of noble Utopian thinking maintained by a few big-hearted, naïve people. On the contrary, it is a determining factor of the quality of our existence, now and to come. We must have the insight to recognize this and the audacity to proclaim it. The altruism revolution is on its way. Let us all be part of it.” - Matthieu Ricard

Guided Mindfulness Meditation with Thích Nhất Hạnh: • The Practice of Mindfulness Meditation... The Chi Center ~ Beginning Qigong Practice ♡ With Master Mingtong Gu ♡ Wisdom Healing Qigong ♡: • The Chi Center ♡ Beginning Qigong Pra... Awakening the Heart ~ by Thich Nhat Hanh ~ The Practice of Inner Transformation: • Awakening the Heart ♡ The Practice of...

“When a rainbow appears vividly in the sky, you can see its beautiful colors, yet you could not wear as clothing or put it on as an ornament. It arises through the conjunction of various factors, but there is nothing about it that can be grasped. Likewise, thoughts that arise in the mind have no tangible existence or intrinsic solidity. There is no logical reason why thoughts, which have no substance, should have so much power over you, nor is there any reason why you should become their slave.” - Dilgo Khyentse Rinpoche

“Using your anger to grow the lotus of peace, of joy, of forgiveness” - Thích Nhất Hạnh

• Using your anger to grow the lotus of... Awakening the Luminous Mind by Geshe Tenzin Wangyal Rinpoche: • Awakening the Luminous Mind by Geshe ... #GlobalWellBeing

• Global Well-Being, Sept. 28, 2016; CC Liu, Amber Larson (eds.), Wisdom Quarterly

Soldier karma: life with NO brain

Psychology of brain damage: shattered

How can we live in a world that makes no sense at all? How could we exist when every second of our lives is an unsolvable puzzle, and the tiny bits we do manage to recognize can’t come out?

That was the life of Russian soldier Lev Zasetsky (1920–1993), a young man who suffered a brain injury fighting in another useless war.

That was the life of Lev Zasetsky, who suffered a severe brain injury when thrown into World War II.

The 3,000-page diary he wrote following his injury became one of the most valuable and insightful texts on the study of the human brain in the history of biological science (popsci.com).

Zasetsky suffered from aphasia, a disorder or dysphasia that impairs a person’s ability to communicate or understand communication.

• When Monkey Mind (thinking) stopped
• Case of survival: Lev Zasetsky | Mind Matters
• VIDEO: What if brain stopped working for 5 seconds?

Patient Lev Zasetsky and Dr. Alex Luria

Zasetsky’s form of aphasia resulted in him being able to write without being able to read his own writing or understand all of what he had written.

Russian Dr. Alexander Luria, one of the Soviet Union’s most accomplished neuropsychologists, was assigned to care for Zasetsky and found that the young soldier “simply could not write and…had suddenly become illiterate.”

Dr. Luria pinpointed Zasetsky’s injury to “the second major block of the brain located in the posterior sections of the large hemispheres.”

This portion of the brain’s job is “for receiving, processing, and retaining information a person derives from the external world.”

The precise location of his shrapnel injury meant that “a very important function [had] been seriously impaired: he [could] not immediately combine his impressions into a coherent whole; his world [became] fragmented.”

That’s how the world existed for Lev Zasetsky: fragmented. But he didn’t give up. His fascinating story and undaunted attitude can inspire and reframe our modern understanding of psychology, history, language, communication, showing what the human spirit can accomplish.

• From "He was the man who lived with no brain" (sort of), Popular Science, for more original Popular Science videos, subscribe on YouTube

SUTRA: Want to be a soldier? You might want to reconsider

The headman (gamini) was wise to ask the Buddha to clarify and dispel doubts (Yodhājīva Sutta)

 

The village headman Yodhajiva went to the Buddha, bowed, sat respectfully to one side, and said: "Venerable sir, I have heard it passed down through the ancient teaching lineage of warriors that:

• 'When a warrior strives and exerts in battle, if others strike one down and slay one while striving and exerting in battle then, with the breakup of the body after death, one is reborn in the company of angels (devas) slain in battle.'

"What does the Blessed One say about that?"

"Enough, headman, set that question aside and do not ask it." But a second time and third time the headman Yodhajiva asked it.

"Headman, I seem to be unable to get past by saying, 'Enough, headman, set that question aside and do not ask it,' so to reply simply: When a warrior strives and exerts in battle, one's mind is already seized, debased, and misdirected by the thought, 'May those beings be struck down, slaughtered, destroyed, annihilated, and no longer exist.'

"If others then strike one down or slay one while one is striving and exerting in battle, then with the breakup of the body after death, one is reborn in a hell called the Realm of those Slain in Battle.

Oh no, what will come of ignorance and killing?

"Moreover, if one holds a view such as, 'When a warrior strives and exerts in battle, if others then strike one down or slay one while one is striving and exerting in battle, then with the breakup of the body after death, one is reborn in the company of angels slain in battle,' that is his wrong view.

"There are, I say, two destinations for a person with wrong view, either hell or the animal womb" [rebirth in one of the many hells or the super-diversified animal plane].

When this was said, the headman Yodhajiva began to sob and burst into tears.

"Headman, that is what I was unable to get by you by asking you to set that question aside and not ask it."

"But, venerable sir, I am not crying because of what the Blessed One said but rather because I have been deceived, cheated, and fooled for a long time by that ancient teaching lineage of warriors who said that" (SN 42.3).

Tiny 'brains' found between brain cells

This bulge of brain cells should not be that hard to understand. What we need are tools.

Behold, the physical base of consciousness? NO

Between and around the billions of neurons in the human brain is an equally vital scaffold, the extracellular matrix (ECM).

An interlinked net of proteins and sugars that surrounds brain cells, the ECM is more than simple structural support; changes in the ECM can regulate complex brain functions including memory, learning, and behavior.

Buddha's Brain (Rick Hanson)

But studies of the brain's ECM have been limited by the lack of tools to observe dynamic changes to its structure. Now, a new genetic labeling tool developed by University of Utah Health researchers Dr. Igal Sterin, Ph.D. and Dr. Sungjin Park, Ph.D. has revealed new patterns in brain ECM in mice, including differences in the amount of matrix deposited on different types of neurons.

A major advantage of the tool is that it can detect changes in the ECM over time, giving new insights into how the brain develops.

The research is published in The Journal of Neuroscience.

• In biology, the extracellular matrix (ECM) [1, 2] also called intercellular matrix (ICM), is a network consisting of extracellular macromolecules and minerals, such as collagen, enzymes, glycoproteins, and hydroxyapatite that provide structural and biochemical support to surrounding [brain] cells [called neurons] [3, 4, 5]. Because multicellularity evolved independently in different multicellular lineages, the composition of ECM varies between multicellular structures; however, cell adhesion, cell-to-cell communication, and differentiation are common functions of the ECM [6]. More: extracellular matrix

Hacking of the American Mind (How? Dopamine)

The new tool has two main parts -- a protein that binds to the main ingredients of the brain ECM fused to another protein that irreversibly sticks to a variety of synthetic fluorescent dyes.

When scientists introduced the tool into neurons, it bound to the surrounding matrix. They then added a fluorescent dye to make matrix structures visible.

Using this tool, the researchers were able to watch as ECM was deposited over time in cultured rodent brain cells, making out dense clusters of matrix that appeared on only certain neurons and at different times.

More on this breakthrough: New tool reveals details of the microscopic brain structures between neurons

• Fluorescent microscopy image of a section of mouse brain, where green is a conventional brain ECM marker. Magenta is the new tool developed by the researchers. Credit: The Journal of Neuroscience (2024). DOI: 10.1523/JNEUROSCI.0666-24.2024.
• The Practical Neuroscience of Buddha's Brain: Happiness, Love, & Wisdom by Dr. Rick Hanson
• The Hacking of the American Mind by Dr. Robert Lustig, M.D.